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doi: 10.1016/j.cell.2011.11.031 126 GuoJGuoZHuangYMaSYanBPanCet al

Briefly, the Griess reagent was prepared by mixing equal volumes of N-(1-naphthyl) ethylenediamine (Component A) and sulfanilic acid (Component B) solution

The experimental procedure was based on the protocol described by (Gregory and Pfaff 1971)

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These virus-induced vesicles could damage mitochondrial membrane integrity, release mt-DNA into circulation, compromise innate immunity, and trigger an exacerbated pro-inflammatory response in COVID-19 patients 164