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Itoh et al., 2004

Plasma Concentration: From ~200 ng/mL to ~80 ng/mL Research measuring GHK-Cu across different age groups has found plasma concentrations of roughly 200 ng/mL around age 20, falling to approximately 80 ng/mL by age 60 a decline of more than 50% over four decades

It is metabolized into several peptide fragments, primarily involving proline-rich sequences, and eliminated with a half-life under 30 minutes

Practitioners should advise patients to select reputable collagen brands and read labels carefully to minimize any adverse side effects of collagen peptides

Vendors should ship lyophilized product with appropriate cold packs and packaging