Supporting that pool is thought to be relevant to mitochondrial efficiency a connection that overlaps with the broader longevity and cellular health research base
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Over time, the genome becomes increasingly dysregulated: DNA regions that should be silent become noisy, protective genes are switched off, and chromatin, the scaffold of DNA wrapped around histones (imagine them like packaging bundles), becomes condensed and brittle, losing its flexibility
If symptoms are severe, worsening, or accompanied by vision changes or systemic signs, prompt medical attention is necessary
(ISBN: 978-0-7817-5009-7).
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