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[4] Fortunately, using MB in the low oral doses provided by 2.5 mg-5 mg capsules is unlikely to cause these severe hematologic issues in patients with normal enzyme function
Manufacturing processes, impurity management, dose accuracy, and injection equipment stability directly affect treatment effects and side effects
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The involvement of GLP-1 in PD can be simplified to the activation of the MAPK/extracellular signal-regulated kinase 1/2 (ERK) pathway, which has an important role in synaptic plasticity, and the PI3K/Akt pathway signaled by GLP-1 receptor stimulation and the subsequent increase in cAMP and PKA and PI3K activation [73]
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He also raises a structural concern
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