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It is often avoided because of weight gain concerns, but the mechanism is more nuanced than that label suggests
This growing body of human data on GLP-1 therapies and thyroid cancer now includes large observational studies, post-marketing safety reports, and long-term cardiovascular outcome trials
The cardiovascular outcomes trial SUSTAIN-6, which enrolled over 3,000 patients with type 2 diabetes at high cardiovascular risk, actually demonstrated cardiovascular benefits with semaglutide, including reduced rates of major adverse cardiovascular events
The choice between the two forms can thus be made based on patient preference and lifestyle considerations, without compromising on efficacy and safety outcomes
Am J Case Rep (2011) 12:314
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