Some patients report that by varying the dose and missing a couple of days they have experienced better results, due to drug tolerance issues
Decreased immune activity in the tumor microenvironment could contribute to poor prognosis and an inability to mitigate tumor growth, potentially due to immunosuppression by cancer cells or other immunosuppressive populations in the tumor microenvironment (42)
Dehydration and Electrolyte Imbalance Nausea, vomiting, and diarrhea increase the risk of dehydration
F., Abatemarco, M., Sandes, S
Nrregaard, P
If the cell cannot recycle GSSG back into GSH fast enough using an enzyme called glutathione reductase, the cell enters a state of toxic oxidative stress, leading to mitochondrial damage and, eventually, programmed cell death (apoptosis)