Titration and Finding the Optimal Dosage After four weeks, the dose is reviewed and often increased to 0.5 mg weekly
[10] [11] Clinical trials have shown that semaglutide can cause small mean increases in resting heart rate (typically a few beats per minute)

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Some mild, and, in very rare cases, it can lead to severe side effects and the discontinuation of the drug
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What's more, these medication types also act centrally in the brain to reduce thirst