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Senescent immune cells under excessive loading contribute to age-related pathological changes, which can progress to age-related diseases

Lets break down what that means

Cleveland Clinic explains that GLP-1 agonists can make food stay in the stomach longer and reduce appetite, but they can also cause digestive side effects like nausea and constipation, which makes food choices more important

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Excess body fat, particularly around the abdomen, increases insulin resistance

Hadidchi emphasizes the importance of evaluating each patients overall health status, including any underlying medical conditions such as type 2 diabetes or high blood pressure that could benefit from weight loss