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Side effects: Lower doses do not eliminate the possibility of nausea, fatigue, dehydration, or blood sugar changes
In rodents, dual agonism decreases renal TGF- by 40% and preserves nephrin expression, effects recapitulated as lower macroalbuminuria in SURPASS-4 [29]
10.1074/jbc.M310711200 14 CavalloG.MetrangoloP.MilaniR.PilatiT.PriimagiA.ResnatiG.et al (2016)
The NAD(+) precursor nicotinamide riboside decreases exercise performance in rats
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