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& Huerva, V
B12 administration may cause rapid optic atrophy in these patients Have polycythemia vera
No clinical trial has tested the exact combination, but the closely related CagriSema (cagrilintide + semaglutide) Phase 3 trial showed that adding amylin to a GLP-1 backbone improves weight loss
Haemoglobin levels begin to rise after about one week, whilst the mean corpuscular volume (MCV), which is typically elevated in B12 deficiency, gradually normalises
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