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Articular cartilage is primarily composed of chondrocytes and extracellular matrix (ECM), which is comprised of water (up to 80% of the wet weight), type II collagen, hyaluronans, and other proteoglycans synthesized by chondrocytes

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Cystine uptake assay The cystine uptake assay was conducted with BioTracker Cystine-FITC Live Cell Dye (#SCT047, Sigma)

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