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doi:10.1056/NEJMoa2107519 Wadden TA, Bailey TS, Billings LK, et al

Furthermore, the trim and fill model did not identify any missing studies, corroborating the robustness of the findings

Several models of inflammation are used to better understand these effects including viral RNA, systemic infection, non-infective systemic inflammation, inflammatory mediators, and cytokines, but the most widely accepted model is lipopolysaccharide (LPS) challenge

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Picardi, A