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In China, approximately 44% of migraine patients experience inadequate symptom relief following acute treatment ( Migraine has a significant genetic component, with heritability estimates ranging from 50 to 80% ( Regarding inducements, sleep disorders are significant precipitating factors for migraine attacks

Although exploratory or post-hoc analyses of randomized trials [21, 22] suggest GLP1 receptor agonists versus placebo may protect against cognitive decline, complementary real-world evidence studies with rigorous methodology and sufficient events have been limited to three studies, [16, 23, 24] and the results are mixed

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BH3 profiling in whole cells by fluorimeter or FACS