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For instance, exosomes derived from thyrocytes, which target dendritic cells and contain TPO, heat shock protein 60, major histocompatibility complex (MHC) class II, and activated dendritic cells, can significantly enhance CD4+ T lymphocyte responses, contributing to the onset and progression of AITD (30)

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Interscapular BAT (iBAT) and epididymal WAT (eWAT) were collected, weighted, and subjected to hematoxylin and eosin (H&E) staining or snap-frozen in liquid nitrogen and stored at 80C until analysis

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