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After the first clinical report of APAP toxicity [22], investigators at the US National Institute of Health developed a mouse model of APAP-induced hepatotoxicity, which mimicked the serious liver injury observed in humans [79]

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Luc-Molm13 cells, at a quantity of 5 10 3 , were intravenously injected into NSG mice via tail vein to establish a xenograft mouse model

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(3-carboxy-2-hydroxy-propyl)trimethylammonium hydroxide inner salt acetate

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