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In 2011, the transmembrane glycoprotein CD44, a cancer stem-like cell marker, and more precisely the CD44 variant (CD44 v ) capable to bind hyaluronan has also been described to interacts and stabilizes system (Figure 1)

A large protein, BPC was claimed in a 1994 US patent (#5,288,708) to have been isolated from both human and animal gastric juice and to exert a wide-range of protective effects in organ injury models

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Considering the fact that pomegranate juice is an important source of UroA, such beneficial effects can be indirectly ascribed to this compound