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Proton pump inhibitors (PPIs) and H2-receptor antagonists reduce stomach acid production, whilst metformin (used for type 2 diabetes) can interfere with B12 absorption
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Common signs of B12 deficiency include: Fatigue Lethargy Headaches Mouth ulcers Changes in vision Brain fog Low energy levels Inconsistent sleep cycles Slow metabolism
A separate analysis in Nature Medicine found that retatrutide produced significant reductions in liver fat content in participants with metabolic dysfunction-associated steatotic liver disease (MASLD), suggesting benefits beyond simple weight reduction
Note: These benefits are based on emerging research
These side effects are temporary and usually subside as the body adjusts to the medication
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