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Anti-Doping Agency (USADA) Mechanistic claims (angiogenesis modulation, nitric oxide pathway, cytoprotection) are preclinical

For wellness professionals, it may eventually become part of a broader longevity toolkit, pending proper validation

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in Nature Medicine demonstrated that blocking NNMT in white adipose tissue increased energy expenditure, reduced fat mass, and improved insulin sensitivity in animal models even without changes in diet or activity (Kraus et al., Nature Medicine )