Several studies undertaken globally show that women with vitamin B12 deficiency in early pregnancy were up to five times more likely to have a child with neural tube defects, such as spina bifida, compared to women with high levels of vitamin B12
Continued mechanistic investigation remains an active area of research
doi:10.5009/gnl18490 Vukojevi J, Vrdoljak B, Malekinui D, et al
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For example, vegans or vegetarians may need to add an extra dose of this vitamin since natural B12 sources mainly come from meat, fish, eggs, and dairy