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Muscle loss occurs as a consequence of the calorie deficit and energy restriction, not from the medication itself

Rapid improvement in glucose control has been associated with temporarily worsened diabetic retinopathy

UNC School of Medicine and UNC Health received funding from The Duke Endowment to launch Bridge to Health, a pilot program led by Timothy Daaleman, MD, and UNC Family Medicine

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Change history 18 September 2025 A Correction to this paper has been published: References Fltou M (2011) Integrated systems physiology: from molecule to function to disease