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In laboratory research settings, IGF-1 LR3 is examined for its involvement in IGF-1 receptormediated signaling pathways, intracellular communication networks, and peptide-regulated cellular processes

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Berberine may also have anti-inflammatory and antioxidant properties that extend beyond glucose control, though clinical significance remains uncertain

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Ohtake N, Saito M, Eto M, Seki K