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Glutamine metabolism and mTORC1 pathway Glutamine metabolism and mammalian target of rapamycin complex 1 (mTORC1) pathway have a tight connection through different mechanisms
The evidence base for GLP-1 agonists in binge eating disorder remains preliminary, with most data coming from case reports, small case series, and secondary analyses rather than large randomized controlled trials specifically designed for BED
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Wegovy: Starts at 0.25mg weekly and increases every 4 weeks Typical maintenance dose: 1.7mg or 2.4mg Mounjaro: Starts at 2.5mg weekly, then increases in 2.5mg steps Maximum dose: 15mg weekly Both drugs require gradual dose escalation (titration) to allow the body to adapt and reduce the risk of side effects
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