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Stacking peptides makes sense when two conditions are met: the compounds work through different mechanisms, and their side effect profiles do not compound each other in dangerous ways

Less than 50% of patients respond favorably to most therapies, and reversibility is influenced by age, sex, BMI, and disease aetiology ( + depletion, or BCAA catabolic impairment may be modifiable before structural remodeling becomes fixed

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Another uncommon and serious side effect is the development of kidney or bladder stones

Swartz RD, Wesley JR, Somermeyer G, Lau K