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Feldman SR, Bhutani T, Dellavalle RP, Merola JF, Givens J, Ofori AO

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This enormous safety margin explains why serious adverse effects remain essentially unreported in the research literature

A relatively new class of drugscalled sodium-glucose cotransporter-2 (SGLT2) inhibitorshave proven beneficial for both diabetic and non-diabetic CKD and appear poised to become a mainstay treatment