However, in the exenatide treatment group, the primary outcome rate was 61.2% (n=170), compared to 56.7% in the standard treatment group (n=171), with an adjusted ratio of 1.22 [95% CI, 0.79-1.88] (P=0.38)., which meant that the proportion of subjects who achieved the desired effect in exenatide treatment group was higher (110)
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The relationship between AMPK and GLP1-RA is well-known with special regard to cardiovascular benefits ( Moreover, the link between GLP1-R and cAMP generation has also been investigated with regard to the preservation of function in diabetic kidney disease
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All these parameters need to be normal before initiating the treatment
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