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These effects help regulate blood glucose levels while also supporting appetite control and reduced caloric intake

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GLP-1R is a B class G-protein-coupled receptor abundantly expressed in the pancreas and central nervous system, but also detected in lower levels in the gut, kidneys, lungs, liver, heart, muscle, peripheral nervous system, and other tissues ( GLP-1R mediated effects arise as a consequence of the immediate signaling cascade, which can impact insulin secretion and calcium flux in a rapid post translational modifications based manner (31)

Alm do aumento da insulina circulante, o GLP-1 tambm age: Bloqueando a liberao de glicose do fgado

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