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This review has synthesized the growing body of evidence positioning ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, as a compelling therapeutic avenue for this recalcitrant malignancy
Experiments with human samples were approved by the Research Ethics Committee, the Wako Safety Center in RIKEN (approval number: Wako3 30-4(2))
Ghazanfar, H
A study that compared 24 obese patients with MC-4R deficiency to 80 healthy controls (40 obese and 40 lean) found that those with MC-4R mutations consumed significantly more high-fat meals
Practical Approach to Diagnosis & Management of Lipid Disorders
& Smith, J
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