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This distinction is thought to be significant in astrocytes, whose absorption of synaptic glutamate linked to OH ion counter-transport acidifies their cytoplasm and mitochondrial matrix (Poitry et al., 2000)

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Medicinal chemical properties of successful central nervous system drugs

doi: 10.3390/ijms21113847 44 BacherAEberhardtSFischerMKisKRichterG

Stacking penta deca peptide arginate with other peptides Peptide stacking, the practice of combining multiple peptides in a coordinated protocol, can amplify therapeutic outcomes when compounds with complementary mechanisms are combined thoughtfully