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Patients can usually be divided into two groups when starting GLP-1 RAs: those with depression and those without

[1] [3] Wegovy (semaglutide 2.4mg) is a glucagon-like peptide-1 (GLP-1) receptor agonist licensed in the UK for weight management in adults with obesity (BMI 30kg/m) or overweight (BMI 27kg/m) with weight-related comorbidities

As of May 2026, generic semaglutide retails locally in Canada for roughly $88 to $100 CAD per month at major pharmacies, according to CBC News reporting

Factors like kidney function, tolerance, and treatment goals matter when determining whether this combination is appropriate