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Notably, in sensitivity analyses with linkage to echocardiographic parameters, the association was consistent across the ejection fraction spectrum, with higher FRP HF linked to higher incidence of both HFrEF/HFmrEF and HFpEF events (adjusted HRs: 2.81 [95% CI: 1.04-7.55] vs 3.45 [95% CI: 1.24-9.55] per 25-percentile increments, respectively) (Supplemental Figure 5)

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