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Long-term safety remains a crucial area of focus, particularly in understanding the implications of senescent cell clearance over extended periods
(9) A Nakamura, T Sugao, K Yamaue, M Kobatake, et al (1989) Involvement of spinal noradrenergic system in the mechanism of an antinociceptive effect of delta-sleep-inducing peptide (DSIP) Brain Research, 1989 Feb 20, Volume 480 (Issues 1-2), Pages 82-6
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True transformation begins internally
Comprehensive monitoring should include assessment of therapeutic response and screening for potential adverse effects, particularly signs of malignancy given the angiogenic effects
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