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The anorectic and thermogenic effects of OXM were also demonstrated in overweight and obese humans, where chronic administration with native OXM resulted in modest weight loss without any detectable adverse effects [82,83,84]
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CagriSema has a very nice efficacy in that regard in type 2 diabetes
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By increasing norepinephrine signaling, phentermine reduces the drive to overeat and helps patients feel satisfied sooner during meals
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