When compared to those taking a placebo and with all participants eating a standardized breakfast, people taking semaglutide ate 24% less overall and approximately 35% less during their lunch and evening meals
Vacca, M
2020;53(1):e13644
Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial The COR-I study found that a combination of sustained-release naltrexone and bupropion significantly reduced bodyweight in obese individuals over 56 weeks, with 48% achieving at least a 5% weight loss, while nausea was the most common side effect
How Second Nature can help Second Nature combines medication with a structured habit-change programme built around the balanced plate model: half vegetables, a quarter protein, a quarter complex carbohydrates, plus a serving of healthy fat
ChemMedChem 13: 662671, 2018