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74 For instance, in the Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients (STEP) trial, weekly semaglutide administration resulted in a mean body weight reduction of 14.9% from baseline among overweight or obese non-diabetic individuals, 76 a magnitude of weight loss previously observed only following bariatric surgery

Dose Response and Individual Variation in Tirzepatide Efficacy Clinical trial data demonstrates dose-dependent response: at 5 mg weekly, average weight loss was 15%

Journal of Nephrology

Front Horm Res

The exact reason is not fully understood, but they may be related to changes in appetite, blood sugar levels, hydration or gastrointestinal effects

Wegovy acts on areas of the brain which are involved in regulating your appetite