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Embody GLP-1 reports an average loss of 1.5% of body weight per week at therapeutic doses, which works out to roughly 10 to 20 pounds over 12 weeks for a 200-pound patient

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Sentinel-node biopsy or lymphoscintigraphy, which is beneficial in staging of cutaneous melanoma, has little value in staging or treating oral melanoma

Statistical analysis A sample size of 300 participants provided an effective power of at least 96% for the two co-primary endpoints, and at least 43% for all confirmatory secondary endpoints, which were tested in a predefined hierarchical order (Supplementary Table 4)