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Gpxs are the main enzymes involved in scavenging ROS at high intracellular concentrations, protecting cells from oxidative stress-induced damage
Salah, M., Abdelsamie, A
Nature 2011;481:385-8
Glutathione also impacts the regulation of DNA and protein synthesis, amino acid transport, and gene expression, as well as cell proliferation, and cell death
Superoxide anion, in turn, serves to generate other reactive oxygen species (ROS) that kill the phagocytosed microorganisms
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