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IL-1R1 and TLR4 are expressed in astrocytes and BBB ECs and have been shown to be upregulated in clinical and experimental studies of epilepsy
It works through amylin receptors to slow gastric emptying, suppress post-meal glucagon release, and signal satiety
"The development of small molecule angiotensin IV analogs to treat Alzheimer's and Parkinson's diseases." Progress in Neurobiology
Misfolded amyloid proteins compromise the BBB integrity, impairing its ability to perform its normal functions[41, 42]
In this study, SBA-15 mesoporous silica nanoparticles (SBA-15 MSN) with a potent fluorescence emission were synthesized by a sol-gel method for targeted drug delivery