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A phase 1, randomized, double-blind, placebo-controlled, single- and multiple-dose escalation study to evaluate the safety and pharmacokinetics/pharmacodynamics of PF-06835375, a C-X-C chemokine receptor type 5 directed antibody, in patients with systemic lupus erythematosus or rheumatoid arthritis
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Ratio between the lowest PoD from all EpiAlveolar model readouts (except transcriptomics) in Laboratory 2 and the highest exposure estimate in the lower respiratory tract