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These factors contributed to the technique needing to be more sensitive than other assays

Kevin J Lenton, Alain T San, Hlne Therriault, Andr M Cantin, Hlne Payette, J Richard Wagner - Vitamin C augments lymphocyte glutathione in subjects with ascorbate deficiency - Am J Clin Nutr - 2003 Jan

Blood 60(Suppl1):162a, 1982

Glycine, usually protective, may paradoxically increase oxidative stress

While the liver plays a significant role in systemic glutathione metabolism, the central nervous system (CNS) maintains its own tightly regulated GSH pool, independent of peripheral control (3-4)

In this sense, glutathione is less a single antioxidant than an antioxidant system manager