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Expert Guidance and Support Weight loss isnt just about medication
most of the research has been done on combo treatments
Hence, this autoantibody presence especially targets the autonomic and central nervous systems (503), which may explain the dysautonomia and immune dysregulation present in ME/CFS (58)
When you're dehydrated: Plasma osmolality rises (more concentrated blood) The hypothalamus signals the choroid plexus to reduce CSF production to conserve water Total CSF volume drops from the normal 125-150 mL to as low as 100-110 mL The brain sits lower in the skull with less hydraulic support Position changes create larger pressure differentials A 2020 study in Fluids and Barriers of the CNS (Bothwell et al.) measured CSF production in mildly dehydrated subjects (2% body water loss, equivalent to missing 2-3 glasses of water per day) and found a 17% reduction in CSF turnover rate within 48 hours
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