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Special Precautions Administration of high doses of the oral formulations of levocarnitine for long periods of time is not recommended in patients with severely compromised renal function or in ESRD patients on dialysis due to the fact that major metabolites formed following oral administration trimethylamine (TMA) and trimethylamine-N-oxide (TMAO) will accumulate since they can not be efficiently removed by the kidneys
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It is studied here strictly as a research peptide
On the other hand, since NAC is an acetylated ( in the lab ) compound, which doesn't exist in nature , or only in almost undetectable traces, it is considered as xenobiotic ( not naturally found in the body )
Leone-Bay A, Paton DR, Variano B, Leipold H, Rivera T, Miura-Fraboni J, et al
Those areas consist of: Injection devices and solution dispensers, IV fluids and IV delivery systems, and infusion technology platforms
