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Role of combination antiplatelet and anticoagulation therapy in diabetes mellitus and cardiovascular disease: insights from the COMPASS trial

Following the administration, antigen-presenting cells phagocytosed the TNV, resulting in the exposure of GFLG to cathepsin B, which ultimately leads to the free release of imidazoquinoline to sensitize the TLR7/8, located on the endosomal inner membrane [353]