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Young males displayed also higher NADP + /NADPH ratio in frozen blood compared to age-matched females, while NADH and GSSG were higher and GSH/GSSG ratio lower in 31-40 years old males compared to females (Supplementary figure 2i-s)

doi:10.1155/2016/6757154 20

It provides a more stable, sustained presence of the peptide in the bloodstream rather than a rapid peak and fall, potentially allowing for a more prolonged therapeutic window

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Although p53-induced downregulation of SLC7A11 could partially inhibit cystine uptake, the overall effect on GSH/GSSG ratio and glutathione levels was less

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