Notable DAMPs include High Mobility Group Box 1 (HMGB1), which interacts with TLR-2, TLR-4, TLR-9, and Receptor for Advanced Glycation End products (RAGE)
Some clients decide to have one every three months or just when they have a busy week at work or are going on holiday
If pain becomes more persistent or shows a neuropathic component, tricyclic antidepressants (such as amitriptyline or nortriptyline) or SNRIs (duloxetine, venlafaxine) may be added to stabilize nerve sensitivity and enhance long-term pain control
Georgiou-Siafis SK, Tsiftsoglou AS
Wang W, Yang L, Liu T et al (2020a) Ellagic acid protects mice against sleep deprivation-induced memory impairment and anxiety by inhibiting TLR4 and activating Nrf2
light blue tint possible Notes Discoloration beyond a faint blue-green hint suggests contamination