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Upregulation of SOD2 and antagonism of NMDA receptors can manipulate this vicious cycle (80)

Glutathione Dysregulation and the Etiology and Progression of Human Diseases. Biological chemistry 390.3 (2009): 191214

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Research suggests methylcobalamin stays in the body longer while cyanocobalamin may be more easily absorbed, but other studies have found little difference in the two in absorption and retention