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The prevalence of moderate hyperhomocysteinemia in patients with early onset venous and arterial occlusive disease was almost twice as high when hyperhomocysteinemia was detected by the methionine-loading test as when detected in the fasting state (Fermo et al, 1995)

Alterations in GSH metabolism and function have been implicated in various neurological aging while restoring redox balance and mitigating oxidative damage

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In reality, the reliability of glutathione measurements, unless done under strictly controlled conditions, may be questionable due to its rapid oxidation once blood is taken