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This allowed us to identify a link between raised IGF-I levels and an increased risk for thyroid cancer in this UK cohort. says lead investigator, Dr Anika Knuppel of NDPH

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But the strongest results came from retrospective analyses with major potential for residual confounding, and the signal weakened in the comparison against SGLT2 inhibitors

This has been demonstrated in lung cancer mouse models, chromophobe renal cell carcinoma and colorectal cancer