When considering the combination of these medications, several factors should be taken into account: Overlapping side effects Both medications can cause gastrointestinal symptoms, which may be additive when used together
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Heart Failure with Preserved Ejection Fraction (HFpEF) HFpEF is a complex clinical syndrome, particularly common in individuals with obesity, for which therapeutic options have historically been limited
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Taking the medication with a small meal and avoiding high-fat or spicy foods during the initial weeks helps considerably