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With an investigational compound that has not completed its full safety review, those risks stack on top of each other
Kellie has lost 51 pounds
Liraglutide follows a similar proteolytic cleavage pathway in various tissues, akin to the metabolism of other large proteins
Semaglutide should be stored in a cool environment, typically in a refrigerator
But it is not the only outcome, and in patients with established atherosclerotic disease or heart failure, it may not even be the primary mechanism of benefit
Notes This article was published on June 25, 2021, and updated on July 15, 2021, at NEJM.org
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