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In Locusta migratoria , LmGSTE4 was found to metabolize malathion and DDT
The D form of carnitine, on the other hand, is biologically inactive and isn't sold as a supplement
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This suggests a very good safety and tolerability profile indistinguishable from placebo in those trial settings
Increased GST and/or GT tumor expression, generally considered as a bad prognosis marker (associated with drug resistance and disease progression), and could potentially be used as a predictive marker, allowing doctors, after biopsy, to identify which patients will respond best to GST or GT-activated prodrugs
V., Milyutina, Y
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